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Microsoft AutoUpdate is a software developed by Microsoft for automatically updating its own software. If you have installed the Edge browser, you will also find that this software is installed at the same time. Uninstalling Edge does not uninstall this software.

There are several different methods to uninstall Microsoft AutoUpdate on macOS. Here are some effective methods:

Method 1: Set permissions to not allow access#

1. Open Terminal.

2. Enter the following command and press Enter:

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   cd /Library/Application\ Support/Microsoft/MAU2.0
   sudo chmod 000 Microsoft\ AutoUpdate.app
   

3. Enter your password. This way, Microsoft AutoUpdate.app will no longer have execution permissions [1].

Method 2: Delete Microsoft AutoUpdate#

1. Open Finder.

2. Use the shortcut: command (⌘) + ⇧ + G, or from the top menu, select "Go" - "Go to Folder".

3. In the pop-up dialog, enter the following path and click "Go":

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   /Library/Application Support/Microsoft/
   

4. Delete the folder MAU2.0, or directly delete Microsoft AutoUpdate.app [1][2].

Method 3: Disable notifications through System Preferences#

1. Click on the Apple menu at the top of the screen, and select "System Preferences" > "Notifications".
2. Find Microsoft Update Assistant and turn it off [3].

Method 4: Use MacKeeper to manage app updates#

If you want to manage app updates more efficiently, consider using MacKeeper's Update Tracker feature. This feature can notify you of updates when you click, and allows you to update multiple apps at once [3].

Method 5: Uninstall using AppCleaner#

1. Install and open AppCleaner.
2. Open Finder, press Cmd+Shift+G, paste the path /Library/Application Support/Microsoft/MAU2.0/.
3. Drag Microsoft AutoUpdate.app into AppCleaner to delete it [6].

Choose the method that suits your needs. If you no longer use Microsoft applications or prefer to manually manage the updates for these applications, uninstalling Microsoft AutoUpdate can be a good choice.

Citations:
[1] https://juejin.cn/post/6911190158469496840
[2] https://blog.csdn.net/weixin_50657813/article/details/124475225
[3] https://mackeeper.com/blog/stop-microsoft-autoupdate-on-mac/
[4] https://juejin.cn/post/7091942430777278478
[5] https://osxdaily.com/2019/07/20/how-delete-microsoft-autoupdate-mac/
[6] https://apple.stackexchange.com/questions/428234/how-to-remove-microsoft-autoupdate-from-macos
[7] https://www.macappbox.com/a/1177.html
[8] https://developer.baidu.com/article/details/2686266